Recent mouse models of PD have focused on α-synuclein, either overexpression of normal or mutated α-synuclein under transgene control or overexpression by administration of α-synuclein viral transduction vectors (Watson et al., 2012; Béraud et al., 2013; Gardai et al., 2013; Harms et al., 2013). Here, SNCA is linked to Parkinson disease.