TP53 and colon carcinoma: As a matter of confirmation of an endogenous p53-dependent control of α-syn mRNA transcription in cell lines of human origin, we used the human colon carcinoma HCT116 (Fig. 3e-h) and haploid HAP1 (Additional file 2: Figure S2A-C) cells to compare the parental cell lines that exhibit wild-type p53 (HCT+/+, HAP+/+) to the ones in which p53 gene is disrupted (HCT-/-, HAP-/-).