We detected increased DUSP2 methylation (level ≥5 %) in lung cancer (A427, H322, A549), breast cancer (MCF-7, ZR75-1), melanoma (SKMel13, IGR1, buf1280, SKMel28, MeWo), ovarian cancer (Skov, Ovar, ES2, OAW42), hepatocarcinoma (Hep2G) and sarcoma (LMS6/93, U2OS) cell lines (Fig. 2a and b). This evidence concerns the gene DUSP2 and melanoma.