At the 12q24.12 pleiotropic region, the functional non-synonymous variant rs671 on ALDH2 which encodes the aldehyde dehydrogenase 2 family, has been reported to be associated with coronary artery diseases, blood pressure and alcohol consumption and is common in East-Asian populations in contrast to monomorphic in Europeans [7, 24]. This evidence concerns the gene ALDH2 and coronary artery disorder.