Others reported that syndecan-1 deficiency in mice is associated with increased leukocyte recruitment in TNFα-stimulated retinal and mesenteric microcirculation [28], naïve cremasteric venules [46], and during experimental autoimmune encephalomyelitis [47], delayed-type hypersensitivity response [48], and anti-glomerular basement membrane nephritis [49]. This evidence concerns the gene SDC1 and experimental autoimmune encephalomyelitis.