Fifteen variables: sex, age, marital status, history of cryptococcosis, KS diagnosis, (recent) history of TB, weight loss ≥10 %, oral candidiasis, chronic diarrhea, HIV associated dementia, CD4+ T-cell count, hemoglobin concentration, platelet count, total lymphocyte count, and year of ART initiation predicted dropout at P <0.1. The gene discussed is CD4; the disease is dementia.