TGFA and Familial prostate cancer: Zhu et al. reported that miR-152 could potentially controls migration and invasion by targeting TGF-α in prostate cancer cell lines [29]; Jin et al. reported that miR-376c could inhibit cell proliferation and invasion by targeting TGF-α in osteosarcoma [30]; Qin et al. reported that miR-124 may regulates TGF-α-induced EMT in human prostate cancer cells [31].