As expected, we observed significant (all p < 0.001) upregulation of SLC6A3 (fold-change expression: mean 230-fold), NPTX2 (188-fold), TNFAIP6 (100-fold), NDUFA4L2 (78-fold), ENPP3 (42-fold), FABP6 (39-fold), and SPINK13 (26-fold) in ccRCC tissue. The gene discussed is ENPP3; the disease is nonpapillary renal cell carcinoma.