Whereas MCD is known to have a higher incidence in HIV-infected individuals and generally occurs in those with a CD4 T-cell count <0.35 x 109 cells/L, unlike Kaposi’s sarcoma there appears to be no correlation between relapse of MCD and CD4 T-cell count or the use of ART [17]. The gene discussed is CD4; the disease is Kaposi's sarcoma.