In this study, biomarkers of endothelial activation, haemostasis and thrombosis, including angiopoietin 1 and 2 (Ang-1 and Ang-2) levels, VWF antigen, total active VWF, and ADAMTS13, platelet counts, syndecan-1 levels, and ApoA1 levels, were measured among Ugandan children with SM who participated in a clinical trial [16], in order to investigate associations between these processes. The gene discussed is ANGPT1; the disease is systemic mastocytosis.