VEGFA and neoplasm: Despite the efficient blockage of neoangiogenesis, anti-VEGF therapy did not lead to reduced tumor growth (tumor size 1 week after VEGF inhibition: 0.22 mm2 vs 0.22 mm2 in the isotype control group; p>0.05; four mice per group), reflecting current clinical data (Chinot et al., 2014; Taal et al., 2014).