IL10 and Parkinson disease: Moreover, given that the −819 T/C (rs1800872) and −592 A/C (rs1800871) SNPs in IL-10 have been shown to affect IL-10 levels together with prior data indicating that IL-10 production is elevated in PD patients12, 13, 14, 15, our present negative findings regarding these SNPs and cognitive status in PD are somewhat surprising.