When HIV-positive subjects were sorted according to whether or not they had HIV encephalitis (HIVE) at autopsy, the mRNAs were significantly lower than HIV-negatives in the patients without and with HIVE both (by 26 and 23 % for GAD1, 21 and 27 % for GAD2, 20 and 24 % for GJD2; Fig.1g–i). The gene discussed is GAD1; the disease is AIDS dementia complex.