CXCL8 and tuberculosis: Nevertheless, the exact role of IL-8 in the pathogenesis of tuberculosis is not fully understood because the accumulation of neutrophils in the airway can, on the one hand, contribute to eradication of tubercle bacilli and development of dendritic and T cell responses and, on the other hand, lead to pathogen dissemination and pulmonary tissue damage through the release of cytotoxic molecules [30].