These genes play a role in development and cell growth including, Apold1, Aebp2, Eif4a1, Hoxb, Mtpn, Fgf12, Deptor, Nfasc. Our genetic dissection of transcripts modulated by variation in Gstt2 in the BXD population suggests a plausible link between regulation of cell growth pathways and cancer GWAS [79–81] and further investigation is warranted. The gene discussed is APOLD1; the disease is cancer.