On these premises, the aims of the present study were (i) to investigate circulating LEPCs and their possible association with IL‐17 in pSS and (ii) to characterize the lymphatic vasculature and the expression of lymphangiogenic mediators in MSGs from patients with pSS compared with non‐specific chronic sialadenitis (NSCS) and normal MSGs. The gene discussed is IL17A; the disease is peeling skin syndrome.