In parallel, HFD Liraglutide group presented higher dP/dt+ and dP/dt- indexes compared with HFD and CTRL subgroups, while HFD Sitagliptin subgroup showed increased dP/dt+ and dP/dt- indexes compared with HFD, but not to CTRL group, suggesting that cardiovascular disorders associated with high fat diet were reversed with both incretin therapies (Fig 1). This evidence concerns the gene GCG and cardiovascular disorder.