ABCA1 rs2230806 polymorphism was significantly associated with the HDL-C level in Egyptians and Asians, G allele was associated with a decrease in HDL-C levels in CAD patients [24,42,43], However, another study shows that G allele was associated with increased HDL-C levels in obese people [29]. The gene discussed is ABCA1; the disease is coronary artery disorder.