Cellular MYC (c‐MYC, herein referred to as MYC) plays a role in several fundamental functions of cell biology, including the regulation of cell growth and proliferation, metabolism, differentiation, apoptosis, and angiogenesis.1 Not surprisingly, deregulation of MYC is among the most potent activators of tumorigenesis,2 and, although MYC is the most frequently amplified oncogene in human cancers,3 oncogenic mutations in the gene itself are rare. This evidence concerns the gene MYC and cancer.