INS and type 1 diabetes mellitus: More interestingly, 1/96 of the wells screened with a pool of four well-characterised T1D-relevant peptides (preproinsulin (PPI)15–24 (Skowera et al., 2008), insulin β chain (InsB)10–18 (Pinkse et al., 2005), glutamic acid decarboxylase (GAD65)114–123 (Panina-Bordignon et al., 1995), and islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP)265–273 (Jarchum et al., 2008)) was peptide-reactive (Fig. 2A, bottom).