Similarly, compared with having a high level of SHBG, having a low level was associated with 2.20 (95% CI 1.58, 3.07, men) and 2.91 (95% CI 2.07, 4.10, women) times higher odds of mild NAFLD, and with 5.02 (95% CI 3.66, 6.88, men) and 13.78 (95% CI 9.15, 20.73, women) times higher odds of moderate–severe NAFLD in model 1. The gene discussed is SHBG; the disease is metabolic dysfunction-associated steatotic liver disease.