MAPT and early-onset autosomal dominant Alzheimer disease: Our prioritized proteins are also implicated in additional disorders; a search in OMIM (http://omim.org/) reveals that mutations in MAPT encoding the microtubule-associated protein Tau are linked to a number of neurological disorders including Frontotemporal dementia (FTD), Progressive supranuclear palsy 1 (PSNP1), and of course Alzheimer’s disease.