Interestingly, the frequency of intratumoral CD4+IFNγ+ T cells significantly correlated with that of intratumoral CD8+IFNγ+ T lymphocytes as well as of intratumoral CD4+IL17+ T cells in both types of tumor (Supplementary Figure 2), suggesting their coordinated homing to the tumor site. The gene discussed is IL17A; the disease is neoplasm.