SOD1 and sleep apnea syndrome: Whether the increased baroreceptor sensitivity in healthy animals may prove advantageous in mitigating disease-induced impairment of autonomic control of the heart is a promising concept, and we are currently using our hSOD1 overexpressing mice to determine if hSOD1 overexpression can preserve normal afferent, efferent, and central components of the baroreflex arc in the CIH model of sleep apnea.