The purpose of the study was to investigate possible associations between glutathione S-transferases (GSTM1, GSTT1, and GSTP1), superoxide dismutase (MnSOD Ala16Val), glutathione peroxidase (GPX1 Pro198Leu), catalase (CAT C262T) gene polymorphisms, and AML susceptibility in a Romanian population. Here, CAT is linked to acute myeloid leukemia.