The purpose of the study was to investigate possible associations between glutathione S-transferases (GSTM1, GSTT1, and GSTP1), superoxide dismutase (MnSOD Ala16Val), glutathione peroxidase (GPX1 Pro198Leu), catalase (CAT C262T) gene polymorphisms, and AML susceptibility in a Romanian population. The gene discussed is GSTM1; the disease is acute myeloid leukemia.