Using a conservative Bonferroni correction, we replicated eight of the 47 associations: SOCS3, SREBF1, SBNO2, CPT1A, PRR5L, an intergenic region on chromosome 17, and LY6G6E with BMI; and TNXIP1 with T2D, while nominal significance was reached for a further 12 loci associated with BMI (Table 2). This evidence concerns the gene SOCS3 and type 2 diabetes mellitus.