KIF11 and Alzheimer disease: The importance of Eg5 dysfunction might be related to the fact that, from the different kinesins we considered, only Eg5/KIF11 lies in a genetic region associated with increased risk for AD (Ertekin-Taner et al., 2004; Feuk et al., 2005; Prince et al., 2003; Reitz et al., 2012).