According to RGD annotations, there were several genes related to CNS diseases (Abcg2, Ephx2, RGD1563482, Tgfb2, Mal, and Cst3), and 3 genes associated with hypertension (Ephx2, Cst3, and Ltbp2) are found on this list. The gene discussed is CST3; the disease is Hypertension.