To date, the TGF-β (Transforming Growth Factor β), Wnt (wingless-type MMTV (mouse mammary tumor virus))/β-catenin, and Notch (a family of transmembrane proteins) pathways have been strongly implicated in inducing EMT in epithelial cells including breast cancer epithelial cells. The gene discussed is TGFB1; the disease is breast carcinoma.