A recent pilot study suggested γ-H2AX expression in PBMCs as a possible diagnostic as well as disease activity marker for relapsing remitting MS (RRMS), as patients with RRMS exhibited higher levels of γ-H2AX positive cells than healthy controls and levels of γ-H2AX positive cells were associated with MRI measures of disease activity in patients with RRMS [17]. The gene discussed is H2AX; the disease is relapsing-remitting multiple sclerosis.