Patients with CEL had higher numbers of γ-H2AX foci per cell than patients without CEL (p = 0.03) and patients with CEL had a higher percentage of γ-H2AX positive cells (p = 0.03) than patients without CEL (Fig 3A and 3B). Here, H2AX is linked to Chronic Eosinophilic Leukemia, Not Otherwise Specified.