VLDLR and familial hypercholesterolemia: Low density lipoprotein receptor (LDLR) removes from the vessels low density lipoproteins (LDL), which contain cholesterol esters, phospholipids, triglycerides and apolipoproteins [44], and its deficiencies have been previously related with development of hypercholesterolemia and atherosclerotic lesions [45,46].