In total, the MCPH1 c.904_916del allele was genotyped in 1370 breast cancer cases (145 familial cases, 75 young cases diagnosed below the age of 40 years, and 1150 cases unselected for a family history of cancer or age at disease onset) and 1160 healthy geographically matched controls (Table 1). This evidence concerns the gene MCPH1 and breast carcinoma.