Switching the basal insulin regimen to degludec had no significant effect on body weight of patients with either type 1 diabetes mellitus (58.7 ± 11.4 kg at baseline to 57.9 ± 10.8 kg at 12 weeks and 57.5 ± 11.1 kg at 24 weeks) or type 2 diabetes mellitus (66.6 ± 14.7 kg at baseline to 66.8 ± 14.7 kg at week 12 and 66.9 ± 14.6 kg at week 24) (Table 3). The gene discussed is INS; the disease is type 2 diabetes mellitus.