ADCY5 and type 2 diabetes mellitus: In this study, rs79223353 at the ADCY5 locus, rs55783344 at the HNF1A locus and rs79548680 at the PRC1 locus were determined to be significantly associated with T2D (P<6.02 × 10−4; Supplementary Data 1 and Supplementary Fig. 3).