Since hematopoietic stem cells derived from the bone marrow play a major role in vascular homeostasis [29–31], and other studies have reported that hemoglobin plays an important role in the progression of atherosclerosis [32, 33], hemoglobin level significantly correlates with HGF when the bone marrow is activated by endothelial damage induced by hypertension. The gene discussed is HGF; the disease is hypertensive disorder.