Four of these diseases, CORNEAL DYSTROPHY EPITHELIAL BASEMENT MEMBRANE (EBMD; OMIM: 121820), CORNEAL DYSTROPHY GROENOUW TYPE I (CDGG1; OMIM: 121900), CORNEAL DYSTROPHY LATTICE TYPE I (LCD1; OMIM: 122200) and LUBS X-LINKED MENTAL RETARDATION SYNDROME (MRXSL; OMIM: 300260) have their predicted domains exactly mapped to their only known genes in the OMIM database, while the other 4 diseases have extra predictions of genes that are unknown to be associated with these diseases before. Here, MECP2 is linked to epithelial basement membrane dystrophy.