The hierarchical unsupervised clustering (Supplementary Fig. 4a) distinguished two main branches (i) the first one consisting of three subgroups made of medulloblastomas, neuroblastomas and a subset of intracranial Smarcb1-deficient tumours (a group hereafter referred to as mIC), and (ii) the second one consisting of two subgroups, one made of Smarcb1-deficient lymphomas only, and the last one made of the two extracranial tumours and the remaining intracranial tumours (a group hereafter referred to as mE/IC). The gene discussed is SMARCB1; the disease is neuroblastoma.