Our results that socioeconomic, geographic, and racial factors, as well as diagnostic age, marital status, receiving of radiotherapy, and education level of patients are influential factors for the utilization of postmastectomy reconstruction is highly consistent with reports of previous population-based or multi-institutional studies.11–14,16,17 A new finding was the impact of breast cancer subtype defined by immunohistochemistry HR and HER2 status on the nationwide trends in immediate breast reconstruction. Here, ERBB2 is linked to breast cancer.