Green tea polyphenol (–)‐epigallocatechin‐3‐O‐gallate increases cGMP to inhibit tumor growth by activating apoptotic signaling via the Akt/eNOS/NO/cGMP/PKCδ pathway in multiple myeloma, gastric, pancreatic, and prostate cancers 25. The gene discussed is AKT1; the disease is Familial prostate cancer.