IFNG and infection: Finally, while production of IFN-γ was significantly higher in the reinfected group only at the late stage of the third infection (12th days) when compared to single-infected and control animals (Fig 8F), TNF-α production followed the IL-17A profile, where reinfected animals presented higher cytokine production from the 4th day after the multiple exposure to the parasite (Fig 8G).