This study has evaluated nine polymorphisms of theSlc11a1/Nramp1 gene [(GT)n, 274C/T, 469+14G/C, 577-18G/A, 823C/T,1029 C/T, 1465-85G/A, 1703G/A, and 1729+55del4] in 86 leprosy patients (67 and 19patients had the multibacillary and the paucibacillary clinical forms of the disease,respectively), and 239 healthy controls matched by age, gender, and ethnicity. This evidence concerns the gene SLC11A1 and leprosy.