When tested in 3 bioassays that are regarded as important criteria to measure tumorigenesis and capability of metastasis of cancer cells in in vitro [22], we showed (Fig. 2) that high levels of suppression of PPARγ in PC3-M cells (PC3-M-PPARγ-si-H) produced significant reductions in cell proliferation rate, invasiveness, and anchorage-independent growth. Here, PPARG is linked to cancer.