Figure 3E showed that the number of lymphoid follicles in inguinal lymph node, the level of CD44 that is one of import biomarkers in lymphatic node metastasis, and the level of GFP that is one of the tags of PLCγ1-transformed cells, were all reduced in tumor tissue, exhibiting the lymphatic node metastasis of gastric adenocarcinoma cells (**P < 0.01, ***P < 0.001, vs control). Here, PLCG1 is linked to gastric adenocarcinoma.