PLCG1 and gastric adenocarcinoma: In view of the relationship between growth factors and PLCγ activation [4–7], and our data of the alternation of EMT associated signal molecules at protein and mRNA levels in BGC-823 cells with the transduction by PLCγ1 shRNA vector, we proposed that PLCγ has a promoting effect on the EMT progression in human gastric adenocarcinoma.