TRPC3 and atrial fibrillation: 2010; Davis et al. 2012; Harada et al. 2012; Adapala et al. 2013). In addition, TRPC3 and TRPM7 were upregulated in AF fibroblasts, and might thus contribute to the pathophysiology of the disease (Du et al. 2010; Harada et al. 2012).