Albumin To prevenT Infection in chronic liveR failurE (ATTIRE) incorporates a phase II single-arm multicentre feasibility trial (n=80) prior to a phase III randomised controlled trial (RCT) (n=866) assessing the impact of treatment on the incidence of nosocomial infections, organ dysfunction and mortality in patients admitted to hospital with AD of liver cirrhosis. Here, ALB is linked to cirrhosis of liver.