Although the authors did not examine associations of the score with risk of T2DM itself, they demonstrated causal associations of higher BMI with higher fasting plasma glucose, higher post-oral glucose tolerance test (OGTT) plasma glucose, higher haemoglobin A1c (HbA1c), and higher fasting insulin, suggesting a strong relationship of BMI with a dysglycaemic phenotype. Here, INS is linked to type 2 diabetes mellitus.