While hypogammaglobulinemia is required to diagnose Good syndrome and has been observed in all reported cases to date, including our patient, it is noteworthy that the total CD4+ T cell count was somewhat decreased in five of the eight previously reported cases with Good syndrome and CMVR (Table 3), indicating that partial CD4+ T cell depletion does occur in patients with Good syndrome and suggesting the possibility that selective loss of CMV-targeting CD4+ T cells may have occurred in our patient, facilitating the development of retinitis. Here, CD4 is linked to retinitis.