TLR2 and gastric cancer: Interestingly, genetic ablation of Myd88 in Gp130F/F animals suppressed tumorigenesis to a level comparable with Gp130F/F;Tlr2−/− mice, while the tumor burden of Gp130F/F;Mal−/− compound mutants remained similar to that of their Gp130F/F littermates.135 Given the interest in developing small molecular inhibitors against TLR2 for human GC,136, 137 the use of the Gp130F/F mouse as a model for the testing of anti‐TLR2 molecules has already shown favorable results.131