Consequently, bacterial overgrowth can occur, which promotes inflammation and other pathophysiological changes.7 Indeed, gastrin‐deficient mice, which have achlorhydric stomachs, are characterized by bacterial overgrowth and chronic atrophic gastritis that progresses to GC.9 Likewise, Helicobacter felis‐infected wild‐type mice also develop achlorhydria, atrophy, and gastric tumors.10 The gene discussed is GAST; the disease is gastric cancer.