Given that increased gray matter in BPD (compared with control subjects) is likely to be related in a straightforward manner to patterns of increased functional activation, as the blood oxygen level–dependent signal appears to be related most closely to local field potentials, which arise primarily from dendritic membrane potentials in a local region [54], we can reasonably make a hypothesis that increased GMV in MCC might relate to increased activation in MCC, and might be an indicator of deficits in emotional–cognitive interplay in young adult patients with BPD. This evidence concerns the gene MCC and Borderline personality disorder.