Whereas the addition of OxPAPC to the M. smegmatis knock-in strains overexpressing lprP or mpt83 during PBMC infection reversed the enhanced HIV infectivity of isolated CD4+ T cells to levels similar to those following infection with wild-type M. smegmatis, addition of CLI-095 had no such effect on PBMC infected with the mpt83 knock-in strain (Fig 1C). Here, PRR4 is linked to infection.